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Hand hygiene is the best method to prevent the transmission of infections. Hand hygiene for hospitalized patients sounds obvious – something that should be easy to accomplish and regarded as important to the patient experience. However, patient hand hygiene is a problem for most hospitals today. It is difficult to accomplish and not monitored by healthcare personnel. No infection preventionist will argue against the importance of patient hand hygiene. However, since it is neither prioritized nor measured by hospitals, it falls through the cracks. This, coupled with the fact that more and more research points to patients as the “missing link” in infection control efforts means that, in order to reduce hospital acquired infections (HAIs), hospitals need dedicated efforts to improve patient hand hygiene. Key to achieving these efforts is empowering patients to make hand hygiene easy to do on their own and to understand the critical importance cleaning their hands plays in preventative care.